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Silicone-free solution enables more challenging sensitive biologics to be administered in a pre-filled syringe
March 27, 2019
By: Kristin Brooks
Managing Editor, Contract Pharma
W.L. Gore & Associates, Inc. has launched the GORE ImproJect Plunger for Pre-Filled Syringes, a solution for silicone-sensitive biologics. Conventional pre-filled syringe systems use silicone to help provide a seal and to act as a lubricant between the barrel and the plunger. However, silicone can impact drug stability for some highly complex and sensitive biologics. Silicone oil has been shown to cause aggregation and particle formation in therapeutic proteins, and silicone m...
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